| Chemical Properties | yellow powder |
Chemical Properties| Auramine is a yellow crystalline powder orflaky material. |
| Uses | Certified for use by fluorescence microscopy in Churukian's modification of Truant's fluorescent method for acid fast bacilli on paraffin sections. |
Uses| Fluorescent stain for acid-resistant bacteria in sputum |
| Definition | ChEBI: A hydrochloride obtained by combining 4,4'-carbonimidoylbis(N,N-dimethylaniline) with one molar equivalent of hydrogen chloride. A fluorescent stain for demonstrating acid fast organisms in a method similar to the Zieh Neelsen. It also can be used to make a fluorescent Schiff reagent. |
General Description| Yellow flakes or powder. |
| Air & Water Reactions | Insoluble in water. |
Reactivity Profile| AURAMINE O is incompatible with strong oxidizing agents. |
| Hazard | Probable carcinogen. |
Fire Hazard| Flash point data for AURAMINE O are not available. AURAMINE O is probably combustible. |
| Biological Activity | Auramine O is used for the staining of acid-fast organisms, coccidia. Auramine O along with carbol generates brilliant yellow fluorochrome of tubercle bacilli. It is effective in detecting positive cases of tuberculosis. Auramine O binds to the mycolic acid in the bacterial cell wall. |
Potential Exposure| Auramine is used industrially as a dyeor dye intermediate for coloring textiles; paper, and leather.Also used as an antiseptic (a powerful antiseptic in ear andnose surgery, and treatment of gonorrhea) and fungicide.Human exposure to auramine occurs principally throughskin absorption or inhalation of vapors. Low-level dermalexposure to the consumer may occur but would be limitedto any migration of auramine from fabric, leather, or papergoods. |
| Shipping | UN2811 Toxic solids, organic, n.o.s., HazardClass: 6.1; Labels: 6.1-Poisonous materials, TechnicalName Required. UN3143 Dyes, solid, toxic, n.o.s. or Dyeintermediates, solid, toxic, n.o.s., Hazard Class: 6.1;Labels: 6.1-Poisonous materials, Technical Name Required. |
Properties and Applications | TEST ITEMS | SPECIFICATION | | APPEARANCE | DARK YELLOWPOWDER | | SHADE | BRIGHT YELLOWISH | | HEAT RESISTANCE | 280 °C min | | DENSITY | 1.07 g/cm 3 | | WATER FASTNESS | 4-5 | | LIGHT FASTNESS | 1-2 | | BLEACHABILITY (OXIDATIVE) | 4 | | BLEACHABILITY (REDUCTIVE) | 3 | | WATER SOLUBILITY AT 20 °C | 10 g/L min | | WATER INSOLUBLE | 1.0% max | | MOISTURE | 3.0% max | | TINTING STRENGTH | 100-105 % | | WEIGHT METAL TOTAL | 50ppm max | |
| Purification Methods | It crystallises from EtOH as the hydrochloride and is very slightly soluble in CHCl3, UV: 434nm ( 370). The free base (carbinolamine) has m 136o (from *C6H6). [Goldacre & Phillips J Chem Soc 1724 1949, Conrad et al. Biochemistry 9 1540 1970, Beilstein 14 IV 256.] |
Incompatibilities| Incompatible with oxidizers (chlorates,nitrates, peroxides, permanganates, perchlorates, chlorine,bromine, fluorine, etc.); contact may cause fires or explosions.Keep away from alkaline materials, strong bases,strong acids, oxoacids, epoxides. |
| Waste Disposal | Consult with environmentalregulatory agencies for guidance on acceptable disposalpractices. Generators of waste containing this contaminant(≥100 kg/mo) must conform with EPA regulations governingstorage, transportation, treatment, and waste disposal.Incinerate in furnace with afterburner and scrubber. |
Declaration: The products displayed on this website are intended exclusively for industrial applications or scientific research. They are not intended for medical, pharmaceutical, or food use. In accordance with applicable laws and regulations, purchasing organizations must hold valid qualifications and approvals.
