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2-Iodoxybenzoic acid

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Names and Identifiers

Name2-Iodoxybenzoic acid
SynonymsIBX
Iodoxybenzoic aci
2-iodylbenzoic acid
2-Iodoxybenzoic acid
2-(iodooxy)benzoic acid
2-Iodoxybenzoic Acid Stabilized (SIBX)
1-Hydroxy-1.2-benziodoxol-3(1H)-one 1-oxide
1-hydroxy-1lambda~3~,2-benziodoxol-3(1H)-one 1-oxide
SIBX, 1.3-Dihydro-1.3-dioxo-1-hydroxy-1.2-benziodoxole stabilised
2-Iodoxybenzoic Acid (stabilized with Benzoic Acid + Isophthalic Acid)
CAS61717-82-6
EINECS629-407-7
InChIInChI=1/C7H5IO3/c8-11-6-4-2-1-3-5(6)7(9)10/h1-4H,(H,9.10)
InChIKeyCQMJEZQEVXQEJB-UHFFFAOYSA-N

​Physico-chemical Properties

Molecular FormulaC7H5IO4
Molar Mass280.02
Density2.058g/cm3
Melting Point280 °C
Boling Point331.824°C at 760 mmHg
Flash Point154.482°C
Vapor Presure0mmHg at 25°C
AppearanceSolid
ColorWhite to Almost white
Merck14.5048
Storage Conditionunder inert gas (nitrogen or Argon) at 2–8 °C
Refractive Index1.675
MDLMFCD02912492

Risk and Safety

Risk CodesR22 – Harmful if swallowed
R34 – Causes burns
R44 – Risk of explosion if heated under confinement
R42/43 – May cause sensitization by inhalation and skin contact.
R36/37/38 – Irritating to eyes, respiratory system and skin.
R20/21/22 – Harmful by inhalation, in contact with skin and if swallowed.
R37 – Irritating to the respiratory system
R35 – Causes severe burns
R1 – Explosive when dry
Safety DescriptionS26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection.
S45 – In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S22 – Do not breathe dust.
S35 – This material and its container must be disposed of in a safe way.
UN IDsUN 1759 8/PG 2
WGK Germany3
HS Code29163990
Hazard Class8
Packing Group

Reference Information

Use2-iodoylbenzoic acid is used for the oxidation of alcohols in organic synthesis. It is also often used for the preparation of Dess-Martin high iodine.
important oxidant
Main propertiesas an oxidant, the oxidation of primary and secondary alcohols in DMSO exhibits properties similar to those of DMP, when the alcohol has a multifunctional group, IBX has better selectivity than DMP; In addition, DMP is unstable and cannot be stored for a long time, and must be prepared before use, which is inconvenient to use.
ApplicationIBX is an inexpensive, mild oxidant, easy to prepare, and has better selectivity than DMP, can also be used for the preparation of lipid and protein metabolism improving agent oxygen male and so on. The oxidation of alcohols by IBX is usually carried out in DMSO or DMSO/THF solution, simply heating (80 °c) the alcohol, IBX and organic solvents such as ethyl acetate, chloroform, benzene, the mixture of acetonitrile, acetone, dichloromethane and the like can oxidize the primary alcohol and the secondary alcohol to the corresponding aldehyde and ketone. After the reaction is finished, the insoluble by-products and solvents can be removed by filtration to obtain the corresponding carbonyl compound.

 

Declaration: The products displayed on this website are intended exclusively for industrial applications or scientific research. They are not intended for medical, pharmaceutical, or food use. In accordance with applicable laws and regulations, purchasing organizations must hold valid qualifications and approvals.

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