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4-tert-Butylphenol

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4-tert-Butylphenol (4-TBP): Overview and Key Properties

CategoryDetails
Chemical Name4-tert-Butylphenol (4-TBP)
IUPAC Name4-(1.1-Dimethylethyl)phenol
Molecular FormulaC₁₀H₁₄O
CAS Number98-54-4
AppearanceWhite crystalline solid
OdorPhenolic (characteristic)

Physical & Chemical Properties

PropertyValue
Melting Point98–101°C (208–214°F)
Boiling Point237–239°C (459–462°F)
Density (20°C)0.908 g/cm³
SolubilitySlightly soluble in water (0.5 g/L); soluble in ethanol, ether
Flash Point110°C (230°F)

Production Methods

MethodProcess Description
AlkylationPhenol + Isobutylene (acid-catalyzed)
Ion ExchangePhenol + tert-Butyl alcohol (zeolite catalyst)

Applications

IndustryUses
Resins & PolymersIntermediate for phenolic resins, epoxy modifiers
SurfactantsRaw material for nonionic detergents
LubricantsAntioxidant additive
AgrochemicalsPrecursor for pesticides/fungicides
CosmeticsPreservative (regulated use)

Safety & Regulatory Status

ParameterDetails
OSHA PELNot established
Health HazardsSkin/eye irritant; suspected endocrine disruptor
Environmental ImpactToxic to aquatic life (LC50: 2–10 mg/L)
RegulationsREACH registered; restricted in cosmetics (EU)

Comparison with Substituted Phenols

Compound4-TBP vs. Alternatives
PhenolHigher hydrophobicity, lower reactivity
4-NonylphenolLess persistent in environment
Bisphenol ANo estrogenic activity

Market Information

AspectDetails
Global Demand~20.000 tons/year
Price Range$3–5/kg
Major ProducersSI Group, Sasol, DIC Corporation

Key Advantages and Limitations

AdvantagesLimitations
Effective resin modifierEnvironmental toxicity concerns
Stable under heatRestricted in consumer products
Low volatilityRequires careful handling

Summary

4-tert-Butylphenol is a versatile chemical intermediate valued for its hydrophobic properties in resins and surfactants. While industrial demand remains steady, environmental and health concerns are driving research into safer alternatives for sensitive applications.

4-tert-Butylphenol is an organic compound with the chemical formula C₁₀H₁₄O. It consists of a phenol ring (a benzene ring with a hydroxyl group, -OH) and a tert-butyl group (-C(CH₃)₃) attached at the 4-position (para position). This structure makes it a substituted phenol, combining the properties of phenols and bulky alkyl groups.

4-tert-Butylphenol is widely used in the production of resins, polymers, and stabilizers. It is a key intermediate in the synthesis of phenolic resins, which are used in coatings, adhesives, and molding compounds. It is also employed as an antioxidant and UV stabilizer in plastics and rubber. Additionally, it serves as a precursor for fragrances and pharmaceuticals.

The compound is typically a white to pale yellow crystalline solid with a mild phenolic odor. It is toxic and can cause irritation to the skin, eyes, and respiratory system. Proper handling, including the use of personal protective equipment (PPE) and working in a well-ventilated area, is essential. It should be stored in a cool, dry place, away from heat and incompatible materials.

Declaration: The products displayed on this website are intended exclusively for industrial applications or scientific research. They are not intended for medical, pharmaceutical, or food use. In accordance with applicable laws and regulations, purchasing organizations must hold valid qualifications and approvals.

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