1,2,4,5-Tetramethylbenzene

​1,2,4,5-Tetramethylbenzene (Durene)

Chemical Formula: C₁₀H₁₄
Structure: Symmetrical aromatic hydrocarbon with ​four methyl groups (-CH₃) at the ​1, 2, 4, and 5 positions of a benzene ring.

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​Physical Properties

​Appearance: White crystalline solid.​Odor: Mild aromatic odor.​Stability: Highly stable due to symmetrical substitution.

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​Applications

​Organic Synthesis:Intermediate for ​polymers, ​resins, and ​specialty chemicals.​Industrial Chemistry:Production of ​dyes, ​pigments, and ​pharmaceuticals.​High-Performance Polymers:Precursor to ​pyromellitic dianhydride (PMDA), used in ​polyimides (e.g., heat-resistant materials).

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​Safety Considerations ⚠️

​Health Hazards:Causes ​irritation to skin and eyes.​Flammability: Flammable; keep away from open flames or high temperatures.​Storage: Store in a ​cool, dry place to maintain stability.

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Summary:
Durene’s ​symmetrical structure and ​stability make it vital in polymer chemistry and industrial synthesis. Its role in producing high-performance polyimides underscores its technical importance, while proper handling ensures safety due to its flammability.

1.2.4.5-Tetramethylbenzene (Durene) Technical Overview

1. Fundamental Chemical Properties

Property	Specification
Chemical Name	1.2.4.5-Tetramethylbenzene
Common Name	Durene
CAS Number	95-93-2
Molecular Formula	C₁₀H₁₄
Molecular Weight	134.22 g/mol
Appearance	White crystalline solid
Melting Point	79-81°C
Boiling Point	196-198°C
Density (20°C)	0.838 g/cm³
Solubility	Soluble in organic solvents, insoluble in water
Flash Point	73°C

2. Industrial Applications and Characteristics

Application Area	Primary Use
Organic Synthesis	Precursor for polyimide resins
Specialty Chemicals	Intermediate for dyes and pigments
Polymer Industry	Monomer for high-performance polymers
Research & Development	Model compound in crystallography studies
Fuel Additives	Octane booster component

Characteristic	Performance Value
Thermal Stability	Excellent (up to 300°C)
Chemical Reactivity	Moderate (electrophilic substitution)
Purity Requirement	≥98% for most applications
Storage Stability	Stable under inert atmosphere

3. Safety and Handling Guidelines

Safety Aspect	Requirement
Storage Conditions	Cool, dry place away from oxidizers
Personal Protection	Gloves, safety glasses
Fire Fighting Measures	Dry chemical, CO₂, foam
Environmental Impact	Low water solubility reduces aquatic risk
Disposal Method	Incineration or chemical waste facility

1.2.4.5-Tetramethylbenzene is particularly valued in advanced material synthesis due to its symmetrical molecular structure and thermal stability. The compound requires standard aromatic hydrocarbon handling precautions.

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