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Trimethylolamine methane hydrochloride CAS:1185-53-1

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Tris(hydroxymethyl)aminomethane Hydrochloride (Tris-HCl)

CAS No.: 1185-53-1
Molecular Formula: C₄H₁₁NO₃·HCl
Molecular Weight: 157.60 g/mol


1. Basic Properties

ParameterSpecification
AppearanceWhite crystalline powder
Purity (Titration)99.0–101.0%
Solubility (1M aq.)Colorless, clear solution
pH (1% aq.)4.2–5.0
Heavy Metals≤5 ppm
UV Absorbance (1M aq.)≤0.06 (260 nm), ≤0.05 (280 nm)

2. Key Applications

Molecular Biology:Buffer component for DNA/RNA electrophoresis (e.g., TAE, TBE buffers)Protein purification and crystallizationOrganic Synthesis:Intermediate for pharmaceutical compoundsDiagnostics:Buffer agent in IVD reagents

3. Quality Control

TestAcceptance Criteria
Identity (IR)Matches reference spectrum
Water Content (KF)≤1.0%
Endotoxin<0.1 EU/mg (for molecular biology grade)

4. Packaging & Storage

FormSpecification
Packaging25 kg/cardboard drum
Storage– Dry, ≤25°C, ≤60% RH
Shelf Life5 years (unopened)

5. Safety & Handling

Hazard CodePrecaution
H315Causes skin irritation
H319Causes eye irritation
HandlingUse gloves/eye protection

Synonyms:
Tris-HCl | Tromethamine hydrochloride

Declaration: The products displayed on this website are intended exclusively for industrial applications or scientific research. They are not intended for medical, pharmaceutical, or food use. In accordance with applicable laws and regulations, purchasing organizations must hold valid qualifications and approvals.

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