Dithiothreitol CAS No.:3483-12-3

DITHIOTHREITOL (DTT)

CAS No.: 3483-12-3
Molecular Formula: C₄H₁₀O₂S₂
Molecular Weight: 154.25 g/mol

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1. BASIC PROPERTIES

Parameter	Specification
Appearance	White crystalline powder
Purity	≥99.0%
Melting Point	41-44°C (lit.)
Boiling Point	125°C
Density (20°C)	1.04 g/mL
Flash Point	>230°F (>110°C)

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2. APPLICATIONS

Biochemistry:Reduction of protein disulfide bonds (SDS-PAGE sample prep)Cleavage of polyacrylamide gel cross-linkers (bis(acryloyl)cystamine)Neuroscience:Prevention of peptide oxidation (cholecystokinin extraction)Analytical Chemistry:Disulfide bond analysis in protein sequencing

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3. PACKAGING & STORAGE

Form	Specification
Packaging	25 kg/cardboard drum
Storage	– Dry, inert atmosphere
Special Notes	– Hygroscopic
	– Argon blanket recommended for long-term storage

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4. SAFETY & HANDLING

GHS Classification:H315+H319: Causes skin/eye irritationH335: May cause respiratory irritationPrecautions:Handle under nitrogen/vacuum for sensitive applicationsUse desiccated containers

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5. REGULATORY COMPLIANCE

SDS: Available upon requestTransport: Non-hazardous (standard conditions)

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