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Fmoc-L-alpha-phenylglycine

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Fmoc-L-alpha-phenylglycine – Names and Identifiers

NameFmoc-L-alpha-phenylglycine
SynonymsFmoc-Phg-OH
Fmoc-L-phenylglycine
FMoc-(S)-phenylglycine
Fmoc-L-alpha-phenylglycine
(S)-Fmoc-2-aminophenylacetic acid
FMoc-Phg-OH FMoc-L-phenylglycine
N-Fmoc-L-2-phenylglycineFmoc-Phg-OH
[(9H-Fluoren-9-ylmethoxycarbonylamino)]phenylacetic acid
(3-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}phenyl)acetic acid
(2R)-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}(phenyl)ethanoic acid
(2S)-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}(phenyl)ethanoic acid
(S)-2-((((9H-Fluoren-9-yl)Methoxy)carbonyl)aMino)-2-phenylacetic acid
CAS102410-65-1
EINECS1533716-785-6
InChIInChI=1/C23H19NO4/c25-22(26)13-15-6-5-7-16(12-15)24-23(27)28-14-21-19-10-3-1-8-17(19)18-9-2-4-11-20(18)21/h1-12,21H,13-14H2,(H,24,27)(H,25,26)

Fmoc-L-alpha-phenylglycine – Physico-chemical Properties

Molecular FormulaC23H19NO4
Molar Mass373.4
Density1.299±0.06 g/cm3(Predicted)
Melting Point175-180°C
Boling Point606.3±50.0 °C(Predicted)
Specific Rotation(α)81 º (c=1% in DMF)
Flash Point291.103°C
Solubilitysoluble in Methanol
Vapor Presure0mmHg at 25°C
AppearanceWhite crystal
ColorWhite to Almost white
BRN5309005
pKa3.39±0.10(Predicted)
Storage Condition2-8°C
Refractive Index81 ° (C=1, DMF)
MDLMFCD00155632

Fmoc-L-alpha-phenylglycine – Risk and Safety

Safety DescriptionS22 – Do not breathe dust.
S24/25 – Avoid contact with skin and eyes.
WGK Germany3
FLUKA BRAND F CODES10
HS Code2924 29 70
Hazard ClassIRRITANT

Fmoc-L-alpha-phenylglycine – Introduction

Fmoc-L-Phenylglycine is a compound with the chemical formula C28H22N2O5 and a molecular weight of 470.49g/mol. It is an organic amine acid derivative and has important application value.

Fmoc-L-Phenylglycine is commonly used in solid-phase synthesis as part of a synthetic polypeptide chain. It can be synthesized by a solid phase amino acid synthesis method. Solid phase synthesis is a commonly used method of peptide synthesis, in which the amino acids are sequentially fixed on the solid phase material, and the chemical reaction is repeated to construct the polypeptide chain step by step. Fmoc-L-phenylglycine is one of the selective protecting groups (protective group), which can protect the reactivity of the amino group during the synthesis.

For safety information, Fmoc-L-phenylglycine should be stored under dry, dark, low temperature conditions. During operation, attention should be paid to avoid contact with skin and eyes, and good laboratory operating habits and personal protective measures should be maintained. If inhaled, ingested, or in contact with skin, consult a doctor and bring the appropriate Chemical Safety Data Sheet (CSDS).

To sum up, Fmoc-L-phenylglycine is an organic amine acid derivative commonly used in solid-phase synthesis, which has important application value. In chemical synthesis, attention should be paid to safe use and correct operating procedures should be followed.,Disclaimer: The above content is for reference and communication only among industry insiders, and does not guarantee its accuracy or completeness. According to relevant laws and regulations and the regulations of this website, units or individuals who purchase related items should obtain valid qualifications and qualification conditions.

Declaration: The products displayed on this website are intended exclusively for industrial applications or scientific research. They are not intended for medical, pharmaceutical, or food use. In accordance with applicable laws and regulations, purchasing organizations must hold valid qualifications and approvals.

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