4-[4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl]-3-(hydroxymethyl)-benzonitrile monohydrobrom

4-[4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl]-3-(hydroxymethyl)-benzonitrile monohydrobromide – Names and Identifiers

4-[4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl]-3-(hydroxymethyl)-benzonitrile monohydrobromide – Physico-chemical Properties

4-[4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl]-3-(hydroxymethyl)-benzonitrile monohydrobromide – Introduction

4-[4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl]-3-(hydroxymethyl)-benzonitrile hydrobromide is an organic compound with the formula C15H20FNO2. HBr. The following is a description of its nature, use, preparation and safety information:

Nature:

1. Appearance: white or almost white crystalline powder.

2. melting point: about 180-190 degrees Celsius.

3. Solubility: Soluble in water, methanol, ethanol and ether solvents.

Use:

1. pharmaceutical use: the compound is a drug intermediate, often used in the synthesis of biologically active compounds.

2. Chemical research: In organic synthesis, the compound can be used for hydroxyl protection, amino protection and esterification reactions.

Preparation Method:

A commonly used method is to obtain 4-(4-fluorophenyl)-1-(4-fluorophenyl)-butanol by reacting 4-aminobutanone with 4-fluorobenzaldehyde. Then, 4-(4-fluorophenyl)-1-(4-fluorophenyl)-butanol is reacted with an aminomethyl bromide compound to produce the target compound.

Safety Information:

1. the compound belongs to organic compounds, need to be careful operation, avoid contact with skin and inhalation.

2. During use, wear appropriate personal protective equipment, such as gloves, glasses and protective masks.

3. When encountering a fire source, it can cause combustion or explosion. Keep away from open fire and high temperature.

4. storage should be sealed, in a cool, dry place, away from oxidants and acids.

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