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Fludarabine

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Feature Good stability
Classification Chemicals
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Molecular Formula: C10H12FN5O4

Molecular Weight: 285.23

CAS No.: 21679-14-1

Description It is a white or almost white crystalline powder. It is soluble in water, insoluble in organic solvents.

NameFludarabine
Synonymsf-ara-a
NSC 118218
Fludarabine
NSC 118218H
Fludarabine base
Fludarabine(base)
2-Fluoroadeninearabinoside
9-beta-D-Arabinofuranosyl-2-fluoroadenine
9-bata-D-Arabinofuranosyl-2-fluoroadenine
9-beta-d-arabinofuranosyl-2-fluoro-adenin
2-Fluoroadenine-9-bata-D-arabinofuranoside
6-AMINO-9 BETA-D-ARABINOFURANOSYLFLUOROPURINE
9–D-Arabinofuranosyl-2-fluoro-9H-purin-6-amine
9-beta-d-arabinofuranosyl-2-fluoro-9h-purin-6-amin
9-(beta-D-arabinofuranosyl)-2-fluoro-9H-purin-6-amine

Physico-chemical Properties

Molecular FormulaC10H12FN5O4
Molar Mass285.23
Density2.17±0.1 g/cm3(Predicted)
Melting Point265-268°C
Boling Point747.3±70.0 °C(Predicted)
Specific Rotation(α)D25 +17 ±2.5° (c = 0.1 in ethanol)
Flash Point405.8°C
Water SolubilitySoluble in DMF, DMSO, methanol or ethanol. Sparingly soluble in water
SolubilitySoluble in (<1 mg/mL,25°C), DMSO (57 mg/mL,25°C), and ethanol (<1 mg/mL,25°C).
Vapor Presure1.86E-23mmHg at 25°C
AppearanceWhite or white-like crystalline powder
ColorWhite to Pale Yellow
Merck13,4152
BRN1225932
pKa13.05±0.70(Predicted)
Storage Condition2-8°C
StabilityStable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Refractive Index1.876
MDLMFCD00132942
Physical and Chemical PropertiesCrystallization from ethanol-water, melting point 260 °c. [Α] D23 17 ° ± 2.5 °(C = 0.1, ethanol). UV absorption maximum (Ph 1, pH 7, ph 13):262,261,262nm(ε 13200,14800,15000). Difficult to dissolve in water and organic solvents. Fiudarabine 5 ‘-monophosphorate: C10Hl3FN5O7P. [75607-67-9]. Soluble in water.
UseThis product is for scientific research only and shall not be used for other purposes.
TargetSTAT1(Vascular smooth muscle cells)

​ Risk and Safety

Hazard SymbolsXn – Harmful
Risk CodesR23/24/25 – Toxic by inhalation, in contact with skin and if swallowed.
R36/37/38 – Irritating to eyes, respiratory system and skin.
R39/23/24/25 –
R39 – Danger of very serious irreversible effects
R22 – Harmful if swallowed
Safety DescriptionS26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37 – Wear suitable protective clothing and gloves.
S45 – In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S36 – Wear suitable protective clothing.
WGK Germany3
RTECSAU6207000
FLUKA BRAND F CODES10
HS Code29349990

,Disclaimer: The above content is for reference and communication only among industry insiders, and does not guarantee its accuracy or completeness. According to relevant laws and regulations and the regulations of this website, units or individuals who purchase related items should obtain valid qualifications and qualification conditions.

Declaration: The products displayed on this website are intended exclusively for industrial applications or scientific research. They are not intended for medical, pharmaceutical, or food use. In accordance with applicable laws and regulations, purchasing organizations must hold valid qualifications and approvals.

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