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Furosemide CAS No.: 54-31-9

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Molecular Formula: C12H11ClN2O5S

Molecular Weight: 330.7

CAS No.: 54-31-9

NameFurosemide
SynonymsFrusemide
FRUSEMIDE
FUROSEMID
FUROSEMIDE
Furosemide
LABOTEST-BB LT00244801
4-CHLORO-N-FURFURYL-5-SULFAMOYLANTHRANILIC ACID
4-chloro-n-furfuryl-5-sulfamoylanthranilic acid
2-furfurylamino-4-chloro-5-sulfamoylbenzoic acid
2-furfurylamino-4-chloro-5-sulfamoylbenzoic acid
5-(aminosulfonyl)-4-chloro-2-((2-furanylmethyl)amino)benzoic acid
5-[AMINOSULFONYL]-4-CHLORO-2-[(2-FURANYLMETHYL)AMINO]BENZOIC ACID
5-(AMINOSULPHONYL)-4-CHLORO-2-[(2-FURANYLMETHYL)AMINO]BENZOIC ACID
CAS54-31-9
EINECS200-203-6
InChIInChI=1/C12H11ClN2O5S/c13-9-5-10(15-6-7-2-1-3-20-7)8(12(16)17)4-11(9)21(14,18)19/h1-5,15H,6H2,(H,16,17)(H2,14,18,19)
InChIKeyZZUFCTLCJUWOSV-UHFFFAOYSA-N

Physico-chemical Properties

Molecular FormulaC12H11ClN2O5S
Molar Mass330.74
Density1.606
Melting Point220 °C (dec.) (lit.)
Boling Point582.1±60.0 °C(Predicted)
Flash Point11°C
Water SolubilitySoluble in acetone, DMF or methanol. Slightly soluble in water
SolubilityPractically insoluble in water, soluble in acetone, sparingly soluble in ethanol (96 per cent), practically insoluble in methylene chloride. It dissolves in dilute solutions of alkali hydroxides.
Appearancepowder
ColorWhite to Off-White
Merck14,4309
pKapKa 3.8 (Uncertain)
Storage Condition2-8°C
StabilityStable, but light sensitive, air sensitive and hygroscopic. Incompatible with strong oxidizing agents.
Refractive Index1.6580 (estimate)
Physical and Chemical PropertiesDensity 1.606
melting point 220°C
UseUsed as a diuretic

​Risk and Safety

Risk CodesR61 – May cause harm to the unborn child
R39/23/24/25 –
R23/24/25 – Toxic by inhalation, in contact with skin and if swallowed.
R11 – Highly Flammable
R36/37/38 – Irritating to eyes, respiratory system and skin.
Safety DescriptionS7 – Keep container tightly closed.
S16 – Keep away from sources of ignition.
S36/37 – Wear suitable protective clothing and gloves.
S45 – In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S53 – Avoid exposure – obtain special instructions before use.
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection.
S22 – Do not breathe dust.
S36 – Wear suitable protective clothing.
S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
UN IDsUN 1230 3/PG 2
WGK Germany3
RTECSCB2625000
HS Code2935904000
ToxicityLD50 orally in female, male rats: 2600, 2820 mg/kg (Goldenthal)

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