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tert-Butylhydrazine hydrochloride

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1. Overview

PropertyDetails
CAS Number15195-55-6
Chemical Nametert-Butylhydrazine Hydrochloride
SynonymsN-tert-Butylhydrazine HCl; 2-tert-Butyl-1-hydrazine hydrochloride
Primary UsesPharmaceutical intermediates, agrochemical synthesis, and organic synthesis
Productiontert-Butylamine condensation with hydrazine, followed by HCl salt formation

2. Chemical & Physical Properties

AttributeSpecification
Molecular FormulaC₄H₁₂N₂·HCl
Molecular Weight124.62 g/mol
AppearanceWhite to off-white crystalline powder
SolubilityFreely soluble in water; soluble in methanol, ethanol
Melting Point148–152°C
Decomposition Temp.>180°C (with evolution of HCl)

3. Applications

IndustryRole
PharmaceuticalsKey intermediate for antiviral drugs (e.g., remdesivir analogs)
AgrochemicalsSynthesis of herbicides and insecticides
Organic ChemistryBuilding block for heterocycles (pyrazoles, triazoles)
Polymer ScienceChain transfer agent in polymerization reactions

4. Safety & Handling

AspectGuidelines
Hazard ClassificationCorrosive to metals; skin/eye irritant (GHS Category 2A)
StorageInert atmosphere; cool, dry, and ventilated area (<30°C)
IncompatibilityStrong oxidizers, acids (may evolve HCl gas)
PPEGloves, goggles, and chemical-resistant apron

5. Market Dynamics

RegionGrowth Drivers
Asia-PacificExpansion of generic drug manufacturing; agrochemical demand
EuropeRegulatory focus on sustainable synthesis routes
North AmericaInnovation in antiviral therapies; polymer additive development
Global ProjectionExpected CAGR of 5.8% (2025–2031); driven by healthcare and agriculture

Conclusion

tert-Butylhydrazine hydrochloride is a critical intermediary for high-value pharmaceuticals and crop protection agents. Its HCl salt form enhances stability and reactivity in synthesis, making it a preferred reagent in scalable processes. Market growth is underpinned by rising demand for antiviral therapies and sustainable agrochemicals, positioning this compound as a linchpin in modern chemical innovation.

Declaration: The products displayed on this website are intended exclusively for industrial applications or scientific research. They are not intended for medical, pharmaceutical, or food use. In accordance with applicable laws and regulations, purchasing organizations must hold valid qualifications and approvals.

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