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N-acetyl-3-5-diiodo-L-tyrosine

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Classification Chemicals
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N-acetyl-3-5-diiodo-L-tyrosine – Names and Identifiers

NameN-acetyl-3-5-diiodo-L-tyrosine
SynonymsAC-3,5-DIIODO-TYR-OH
N-Acetyl-3,5-diiodotyrosine
N-Acetyl-3,5-diiodo-L-tyrosine
N-ACETYL-3,5-DIIODO-L-TYROSINE
N-acetyl-3-5-diiodo-L-tyrosine
3,5-Diiodo-N-Acetyl-L-Tyrodine
3,5-DIIODO-N-ACETYL-L-TYROSINE
N-Acetyl-3,5-Diiodo-L-tyrosine dihydrate
2-acetamido-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid
2-(Acetylamino)-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid
(2S)-2-acetamido-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid
Levothyroxine Related Compound (N-Acetyl-3,5-Diiodo-L-Tyrosine)
CAS1027-28-7
EINECS213-837-3
InChIInChI=1/C11H11I2NO4/c1-5(15)14-9(11(17)18)4-6-2-7(12)10(16)8(13)3-6/h2-3,9,16H,4H2,1H3,(H,14,15)(H,17,18)/t9-/m0/s1

N-acetyl-3-5-diiodo-L-tyrosine – Physico-chemical Properties

Molecular FormulaC11H11I2NO4
Molar Mass475.02
Density2.206±0.06 g/cm3(Predicted)
Melting Point124.0 to 128.0 °C
Boling Point532.9±50.0 °C(Predicted)
Flash Point276.1°C
Solubilityalmost transparency in Methanol
Vapor Presure3.47E-12mmHg at 25°C
AppearanceCrystallization
ColorWhite to Light yellow to Light orange
pKa2.98±0.10(Predicted)
Storage ConditionKeep in dark place,Sealed in dry,Store in freezer, under -20°C
Refractive Index1.692
MDLMFCD00020004
Physical and Chemical Properties

Property description: white crystalline compound, melting point 178-182 ℃

UseIodothyronin (triiodothyronine) intermediate, pharmaceutical raw material.

N-acetyl-3-5-diiodo-L-tyrosine – Risk and Safety

Safety DescriptionS22 – Do not breathe dust.
S24/25 – Avoid contact with skin and eyes.
WGK Germany3

N-acetyl-3-5-diiodo-L-tyrosine – Introduction

Crystalline compound.

N-acetyl-3-5-diiodo-L-tyrosine – Reference Information

Uses N-acetyl -3, 5-diiodo-L-tyrosine has been used in the simulation system of thyroid hormone biosynthesis. In addition, the ability of N-acetyl -3, 5-diiodo-L-tyrosine to inhibit pepsin-catalyzed hydrolysis was also studied to determine the substrate binding region of the enzyme activity center.
Triiodothyronine intermediate.
production method tyrosine is first iodized with iodine and hydrochloric acid to generate 3,5-diiodotyrosine, and then acylated with acetic anhydride to obtain the product.

,Disclaimer: The above content is for reference and communication only among industry insiders, and does not guarantee its accuracy or completeness. According to relevant laws and regulations and the regulations of this website, units or individuals who purchase related items should obtain valid qualifications and qualification conditions.

Declaration: The products displayed on this website are intended exclusively for industrial applications or scientific research. They are not intended for medical, pharmaceutical, or food use. In accordance with applicable laws and regulations, purchasing organizations must hold valid qualifications and approvals.

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