Imidazole CAS No.288-32-4

Imidazole (CAS No. 288-32-4) 

1. Basic Information

Chemical Name: ImidazoleSynonyms: 1,3-Diaza-2,4-cyclopentadiene; GlyoxalineCAS Number: 288-32-4Molecular Formula: C₃H₄N₂Molecular Weight: 68.08 g/molAppearance: White to pale yellow crystalline solidOdor: Slight ammonia-like odor

2. Physical and Chemical Properties

Melting Point: 89–91 °C (192–196 °F)Boiling Point: 256 °C (493 °F)Density: 1.03 g/cm³ (at 20 °C)Solubility:Water: Highly solubleOrganic solvents: Soluble in ethanol, acetone, chloroform; slightly soluble in etherpKa: 6.95 (weak base, amphoteric)pH: ~10 (1% aqueous solution)Flash Point: 146 °C (closed cup)

3. Chemical Structure

      N       / \      C   C-H     /     \    N       C-H

4. Hazards (GHS Classification)

Health Hazards:Eye/Irritation: Causes severe eye irritation (H319)Skin: May cause irritation (H315)Inhalation: Respiratory irritation possible (H335)Environmental Hazards: Harmful to aquatic life (H402)NFPA Rating: Health 2, Flammability 1, Reactivity 0

5. Storage and Handling

Storage: Keep in a cool, dry place away from strong oxidizers.Handling: Use PPE (gloves, goggles) in well-ventilated areas.

6. Applications

Pharmaceutical intermediates (e.g., antifungal agents).Biological buffer (e.g., in protein purification).Corrosion inhibitor in industrial processes.

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