4-Methyl-3-nitropyridine

4-Methyl-3-nitropyridine (CAS No. 23056-36-2)

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1. Basic Information

IUPAC Name: 4-Methyl-3-nitropyridineSynonyms:3-Nitro-4-picoline3-Nitro-4-methylpyridineCAS Number: 23056-36-2Molecular Formula: C₆H₆N₂O₂Molecular Weight: 138.12 g/molAppearance: Light yellow to tan crystalline powderOdor: Characteristic nitroaromatic odor

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2. Physical and Chemical Properties

Property	Value
Melting Point	52–55°C (126–131°F)
Boiling Point	265–267°C (509–513°F)
Density	1.25 g/cm³ (20°C)
Solubility	– Water: Slightly soluble
	– Organic solvents: Soluble in ethanol, acetone, chloroform
Refractive Index	1.548 (20°C)
Flash Point	115°C (239°F) (closed cup)

 

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3. Hazards (GHS Classification)

Health Hazards:Harmful if swallowed (H302)Causes skin irritation (H315)Causes serious eye irritation (H319)Environmental: Toxic to aquatic life (H411)NFPA Rating: Health 2, Flammability 1, Reactivity 1

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4. Storage and Handling

Storage:Keep in tightly sealed amber containersStore in a cool, dry, well-ventilated areaHandling:Use nitrile gloves, safety goggles, and fume hoodAvoid contact with strong oxidizers

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5. Applications

Pharmaceutical Intermediate: Synthesis of vasodilators and antihypertensive drugsAgrochemicals: Precursor for pyridine-based pesticidesOrganic Synthesis: Building block for heterocyclic compounds

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