Butyryl chloride CAS No.141-75-3

Butyryl Chloride (CAS No. 141-75-3) 

1. Basic Information

Chemical Name: Butyryl chlorideSynonyms: Butanoyl chloride; n-Butyryl chlorideCAS Number: 141-75-3Molecular Formula: C₄H₇ClOMolecular Weight: 106.55 g/molAppearance: Colorless to pale yellow liquidOdor: Pungent, irritating odor (similar to hydrochloric acid)Odor Threshold: <1 ppm

2. Physical and Chemical Properties

Melting Point: -89°C (-128°F)Boiling Point: 101-102°C (214-216°F)Density: 1.028 g/cm³ at 20°CRefractive Index: 1.412 at 20°CSolubility:Reacts violently with water and alcoholsSoluble in ether, acetone, benzeneVapor Pressure: 30 mmHg at 20°CFlash Point: 12°C (54°F) – Highly Flammable

3. Chemical Structure

   O    ║  CH₃-CH₂-CH₂-C-Cl

4. Hazards (GHS Classification)

Flammability: Highly flammable liquid and vapor (H225)Health Hazards:Causes severe skin burns (H314)Causes serious eye damage (H318)Harmful if inhaled (H332)Environmental Hazards: Toxic to aquatic life (H402)NFPA Rating: Health 3, Flammability 2, Reactivity 1

5. Storage and Handling

Storage:Store under nitrogen/argon in a cool, dry place (<25°C)Keep away from moisture, heat, and oxidizersHandling:Use chemical-resistant gloves (neoprene/Viton®)Wear goggles + face shieldWork in a fume hood with adequate ventilation

6. Applications

Pharmaceuticals: Intermediate for drug synthesis (e.g., local anesthetics)Agrochemicals: Production of herbicides and pesticidesPerfumery: Synthesis of butyrate esters (fruity flavors)

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